Integrin activation is an essential component of SARS-CoV-2 infection

Cellular entry of coronaviruses depends on binding of the viral spike (S) protein to a specific cellular receptor, the angiotensin-converting enzyme 2 (ACE2). Furthermore, the viral spike protein expresses an RGD motif, suggesting that cell surface integrins may be attachment co-receptors. However,...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Simons, Peter, Rinaldi, Derek A., Bondu, Virginie, Kell, Alison M., Bradfute, Steven, Lidke, Diane, Buranda, Tione
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312899/
https://ncbi.nlm.nih.gov/pubmed/34312625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.07.20.453118
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