A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity

Foot-and-mouth disease (FMD) is a highly contagious viral disease affecting cloven-hoofed animals that causes a significant economic burden globally. Vaccination is the most effective FMD control strategy. However, FMD virus (FMDV) particles are prone to dissociate when appropriate physical or chemi...

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Bibliographic Details
Published in:J Virol
Main Authors: Dong, Hu, Lu, Yuanlu, Zhang, Yun, Mu, Suyu, Wang, Nan, Du, Ping, Zhi, Xiaoying, Wen, Xiaobo, Wang, Xiangxi, Sun, Shiqi, Zhang, Yanming, Guo, Huichen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312871/
https://ncbi.nlm.nih.gov/pubmed/34011545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00177-21
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