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Tree Shrew Cells Transduced with Human CD4 and CCR5 Support Early Steps of HIV-1 Replication, but Viral Infectivity Is Restricted by APOBEC3

The host range of human immunodeficiency virus type 1 (HIV-1) is narrow. Therefore, using ordinary animal models to study HIV-1 replication, pathogenesis, and therapy is impractical. The lack of applicable animal models for HIV-1 research spurred our investigation on whether tree shrews (Tupaia bela...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Luo, Meng-Ting, Mu, Dan, Yang, Xiang, Luo, Rong-Hua, Zheng, Hong-Yi, Chen, Min, Guo, Ying-Qi, Zheng, Yong-Tang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312864/
https://ncbi.nlm.nih.gov/pubmed/34076481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00020-21
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