3: Multimodal Molecular Analysis Reveals Divergent Trajectories Of Wound Regeneration Versus Fibrosis

PURPOSE: Scarring in the mouse dorsal dermis is mediated by pro-fibrotic, Engrailed-1 lineage-positive fibroblasts (EPFs). We recently showed that mechanotransduction blockade (YAP inhibition, using the drug verteporfin), results in complete wound regeneration, with full recovery of normal dermal ap...

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Détails bibliographiques
Publié dans:Plast Reconstr Surg Glob Open
Auteurs principaux: desJardins-Park, Heather E., Mascharak, Shamik, Januszyk, Michael, Chen, Kellen, Davitt, Michael F., Demeter, Janos, Henn, Dominic, Griffin, Michelle, Bonham, Clark A., Mooney, Nancie, Cheng, Ran, Jackson, Peter K., Wan, Derrick C., Gurtner, Geoffrey C., Longaker, Michael T.
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2021
Sujets:
PSRC 2021 Abstract Supplement
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312805/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.GOX.0000769936.79898.fc
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