QS8: Fat Grafting Depletes Profibrotic Prrx1-positive Fibroblasts In Irradiated Skin And Mitigates Radiation-induced Groin Contracture

PURPOSE: Contracture is a long-term complication of radiotherapy (RT) that results from pathologic fibrosis of soft tissue in the radiation field. Fat grafting can regenerate fibrotic soft tissue by decreasing collagen density and reorganizing collagen fiber networks. Fibroblasts are the predominant...

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Bibliographic Details
Published in:Plast Reconstr Surg Glob Open
Main Authors: Rosealie Borrelli, Mimi, Adem, Sandeep, Griffin, Michelle, Diaz, Nestor, Longaker, Michael T., Wan, Derrick
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2021
Subjects:
PSRC 2021 Abstract Supplement
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312787/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.GOX.0000770132.45355.9e
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