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Aflibercept, a VEGF (Vascular Endothelial Growth Factor)-Trap, Reduces Vascular Permeability and Stroke-Induced Brain Swelling in Obese Mice

BACKGROUND AND PURPOSE: Brain edema is an important underlying pathology in acute stroke, especially when comorbidities are present. VEGF (Vascular endothelial growth factor) signaling is implicated in edema. This study investigated whether obesity impacts VEGF signaling and brain edema, as well as...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stroke
Prif Awduron: Kim, Il-doo, Cave, John W., Cho, Sunghee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312568/
https://ncbi.nlm.nih.gov/pubmed/34192895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.121.034362
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