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Induction of the PPARγ-GCM1 syncytialization axis reduces sFLT1 in the preeclamptic placenta

Preeclampsia (PE) is a hypertensive disorder of pregnancy that is a major cause of maternal-fetal morbidity and mortality worldwide. Severe PE (sPE) is mediated by pathology of the placental villi resulting in repressed PlGF production and hyper-secretion of sFLT1, the net effect being widespread ma...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Armistead, Brooke, Kadam, Leena, Siegwald, Emily, McCarthy, Fergus P, Kingdom, John C., Kohan-Ghadr, Hamid-Reza, Drewlo, Sascha
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312350/
https://ncbi.nlm.nih.gov/pubmed/34024123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.121.17267
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