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NGS-Based ctDNA Profiling After the Resistance of Second-Line Osimertinib for Patient with EGFR-Mutated Pulmonary Adenocarcinoma

Osimertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), is effective in EGFR T790M positive non-small-cell lung cancer (NSCLC). Despite the efficacy of osimertinib, patients inevitably develop resistance and the mechanisms of osimertinib resistance ar...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Li, Dan, Yang, DaFu, Cui, SaiQiong, Pan, Evenki, Yang, Peng, Dai, ZhaoXia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312323/
https://ncbi.nlm.nih.gov/pubmed/34321891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S318250
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