C5 Variant rs10985126 is Associated with Mortality in Patients with Symptomatic Coronary Artery Disease

BACKGROUND: Complement component 5a (C5a) is a highly potent anaphylatoxin with a variety of pro-inflammatory effects. C5a contributes to progression of atherosclerosis and inhibition of the receptor (C5aR) might offer a therapeutic strategy in this regard. Single nucleotide polymorphisms (SNPs) of...

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Bibliografiske detaljer
Udgivet i:Pharmgenomics Pers Med
Main Authors: Henes, Jessica Kristin, Groga-Bada, Patrick, Schaeffeler, Elke, Winter, Stefan, Hack, Luis, Zdanyte, Monika, Mueller, Karin, Droppa, Michal, Stimpfle, Fabian, Gawaz, Meinrad, Langer, Harald, Schwab, Matthias, Geisler, Tobias, Rath, Dominik
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312322/
https://ncbi.nlm.nih.gov/pubmed/34321906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S307827
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