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Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes

OBJECTIVE: Type 1 diabetes (T1D) is an autoimmune disorder in which autoreactive T cells destroy insulin‐producing β‐cells. Interventions that preserve β‐cell function represent a fundamental therapeutic goal in T1D and biomarkers that predict and monitor β‐cell function, and changes in islet autoan...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Musthaffa, Yassmin, Hamilton‐Williams, Emma E, Nel, Hendrik J, Bergot, Anne‐Sophie, Mehdi, Ahmed M, Harris, Mark, Thomas, Ranjeny
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312239/
https://ncbi.nlm.nih.gov/pubmed/34336205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1315
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