Long-term effects of combined B-cell immunomodulation with rituximab and belimumab in severe, refractory systemic lupus erythematosus: 2-year results

BACKGROUND: Anti-CD20 B-cell depletion has not shown superior efficacy to standard immunosuppression in patients with systemic lupus erythematosus (SLE). Besides trial design, potential explanations are incomplete B-cell depletion in relation to substantial surges in B-cell-activating factor (BAFF)....

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Udgivet i:Nephrol Dial Transplant
Main Authors: Kraaij, Tineke, Arends, Eline J, van Dam, Laura S, Kamerling, Sylvia W A, van Daele, Paul L A, Bredewold, Obbo W, Ray, Argho, Bakker, Jaap A, Scherer, Hans U, Huizinga, Tom J W, Rabelink, Ton J, van Kooten, Cees, Teng, Y K Onno
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8311580/
https://ncbi.nlm.nih.gov/pubmed/32591783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfaa117
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