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A new approach for identifying positional isomers of glycans cleaved from monoclonal antibodies
Glycosylation patterns in monoclonal antibodies (mAbs) can vary significantly between different host cell types, and these differences may affect mAbs safety, efficacy, and immunogenicity. Recent studies have demonstrated that glycan isomers with the terminal galactose position on either the Man α1-...
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| Udgivet i: | Analyst |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society of Chemistry
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8311261/ https://ncbi.nlm.nih.gov/pubmed/34231555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1an00780g |
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