Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis

Objective: Aberrations in the PI3K/AKT/mTOR survival pathway in many cancers are the most common genomic abnormalities. The phytochemical and bioactive agent sulforaphane (SFN) has nutrigenomic potential in activating the expression of several cellular protective genes via the transcription factor n...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Mokhtari, Reza Bayat, Qorri, Bessi, Baluch, Narges, Sparaneo, Angelo, Fabrizio, Federico Pio, Muscarella, Lucia Anna, Tyker, Albina, Kumar, Sushil, Cheng, Hai-Ling Margaret, Szewczuk, Myron R., Das, Bikul, Yeger, Herman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2021
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310668/
https://ncbi.nlm.nih.gov/pubmed/34316328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.28011
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