Cellular Uptake and Intracellular Phosphorylation of GS-441524: Implications for Its Effectiveness against COVID-19

GS-441524 is an adenosine analog and the parent nucleoside of the prodrug remdesivir, which has received emergency approval for treatment of COVID-19. Recently, GS-441524 has been proposed to be effective in the treatment of COVID-19, perhaps even being superior to remdesivir for treatment of this d...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Viruses
Autori principali: Rasmussen, Henrik Berg, Jürgens, Gesche, Thomsen, Ragnar, Taboureau, Olivier, Zeth, Kornelius, Hansen, Poul Erik, Hansen, Peter Riis
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310262/
https://ncbi.nlm.nih.gov/pubmed/34372575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13071369
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