Mutation E48K in PB1 Polymerase Subunit Improves Stability of a Candidate Live Attenuated Influenza B Virus Vaccine

Influenza B virus (IBV) is a major respiratory pathogen of humans, particularly in the elderly and children, and vaccines are the most effective way to control it. In previous work, incorporation of two mutations (E580G, S660A) along with the addition of an HA epitope tag in the PB1 segment of B/Bri...

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Publicado en:Vaccines (Basel)
Main Authors: Mo, Jongsuk, Cardenas-Garcia, Stivalis, Santos, Jefferson J. S., Ferreri, Lucas M., Cáceres, C. Joaquín, Geiger, Ginger, Perez, Daniel R., Rajao, Daniela S.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310045/
https://ncbi.nlm.nih.gov/pubmed/34358217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9070800
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