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Harnessing the Natural Biology of Adeno-Associated Virus to Enhance the Efficacy of Cancer Gene Therapy

Adeno-associated virus (AAV) was first characterized as small “defective” contaminant particles in a simian adenovirus preparation in 1965. Since then, a recombinant platform of AAV (rAAV) has become one of the leading candidates for gene therapy applications resulting in two FDA-approved treatments...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Bower, Jacquelyn J., Song, Liujiang, Bastola, Prabhakar, Hirsch, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8309980/
https://ncbi.nlm.nih.gov/pubmed/34201599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13071205
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