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Direct Comparison of the Lowest Effect Concentrations of Mutagenic Reference Substances in Two Ames Test Formats

The Ames assay is the standard assay for identifying DNA-reactive genotoxic substances. Multiple formats are available and the correct choice of an assay protocol is essential for achieving optimal performance, including fit for purpose detection limits and required screening capacity. In the presen...

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Detalhes bibliográficos
Publicado no:Toxics
Main Authors: Rainer, Bernhard, Pinter, Elisabeth, Prielinger, Lukas, Coppola, Chiara, Marin-Kuan, Maricel, Schilter, Benoit, Apprich, Silvia, Tacker, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8309791/
https://ncbi.nlm.nih.gov/pubmed/34209992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxics9070152
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