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Water Uptake by Evaporating pMDI Aerosol Prior to Inhalation Affects Both Regional and Total Deposition in the Respiratory System

As pulmonary drug deposition is a function of aerosol particle size distribution, it is critical that the dynamics of particle formation and maturation in pMDI sprays in the interim between generation and inhalation are fully understood. This paper presents an approach to measure the evaporative and...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Legh-Land, Victoria, Haddrell, Allen E., Lewis, David, Murnane, Darragh, Reid, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8309010/
https://ncbi.nlm.nih.gov/pubmed/34202458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13070941
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