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Differential Effect of Three Macrolide Antibiotics on Cardiac Pathology and Electrophysiology in a Myocardial Infarction Rat Model: Influence on Sodium Nav1.5 Channel Expression

Macrolides were reported to have cardiotoxic effects presented mainly by electrocardiogram (ECG) changes with increased risk in cardiac patients. We aimed to determine the impact of three macrolides, azithromycin, clarithromycin and erythromycin, on cardiac electrophysiology, cardiac enzyme activiti...

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Détails bibliographiques
Publié dans:Pharmaceuticals (Basel)
Auteurs principaux: Farag, Noha E., El-Kherbetawy, Mohamed K., Ismail, Hussein M., Abdelrady, Ahmed M., Toraih, Eman A., Abdelbasset, Walid Kamal, Lashine, Rehab M., EL-dosoky, Mohammed, Abed, Sally Yussef, Ibraheem, Khalid M., Fawzy, Manal S., Zaitone, Sawsan A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308720/
https://ncbi.nlm.nih.gov/pubmed/34206182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14070597
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