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TRK Inhibitors: Tissue-Agnostic Anti-Cancer Drugs

Recently, two tropomycin receptor kinase (Trk) inhibitors, larotrectinib and entrectinib, have been approved for Trk fusion-positive cancer patients. Clinical trials for larotrectinib and entrectinib were performed with patients selected based on the presence of Trk fusion, regardless of cancer type...

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Bibliografiska uppgifter
I publikationen:Pharmaceuticals (Basel)
Huvudupphovsman: Han, Sun-Young
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308490/
https://ncbi.nlm.nih.gov/pubmed/34209967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14070632
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