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Translation Initiation Regulated by RNA-Binding Protein in Mammals: The Modulation of Translation Initiation Complex by Trans-Acting Factors

Protein synthesis is tightly regulated at each step of translation. In particular, the formation of the basic cap-binding complex, eukaryotic initiation factor 4F (eIF4F) complex, on the 5′ cap structure of mRNA is positioned as the rate-limiting step, and various cis-elements on mRNA contribute to...

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Bibliografische gegevens
Gepubliceerd in:Cells
Hoofdauteurs: Fukao, Akira, Tomohiro, Takumi, Fujiwara, Toshinobu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306974/
https://ncbi.nlm.nih.gov/pubmed/34359885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071711
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