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In Silico Analysis of the Longevity and Timeline of Individual Germinal Center Reactions in a Primary Immune Response

Germinal centers (GCs) are transient structures in the secondary lymphoid organs, where B cells undergo affinity maturation to produce high affinity memory and plasma cells. The lifetime of GC responses is a critical factor limiting the extent of affinity maturation and efficiency of antibody respon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Arulraj, Theinmozhi, Binder, Sebastian C., Meyer-Hermann, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306527/
https://ncbi.nlm.nih.gov/pubmed/34359906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071736
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