Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component Shigella GMMA-Based Vaccines

Generalised modules for membrane antigens (GMMA)-based vaccines comprise the outer membrane from genetically modified Gram-negative bacteria containing membrane proteins, phospholipids and lipopolysaccharides. Some lipoproteins and lipopolysaccharides are pyrogens; thus, GMMA-based vaccines are intr...

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Bibliografiske detaljer
Udgivet i:Microorganisms
Main Authors: Carson, Danielle, Myhill, Sophie, Palmieri, Elena, Necchi, Francesca, Rijpkema, Sjoerd, Micoli, Francesca, Nordgren, Ida Karin, Rossi, Omar, Vipond, Caroline
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306433/
https://ncbi.nlm.nih.gov/pubmed/34202832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms9071375
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