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Cell Reprogramming to Model Huntington’s Disease: A Comprehensive Review

Huntington’s disease (HD) is a neurodegenerative disorder characterized by the progressive decline of motor, cognitive, and psychiatric functions. HD results from an autosomal dominant mutation that causes a trinucleotide CAG repeat expansion and the production of mutant Huntingtin protein (mHTT). T...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Monk, Ruth, Connor, Bronwen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306243/
https://ncbi.nlm.nih.gov/pubmed/34206228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071565
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