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Epigenetic reprogramming of cell identity: lessons from development for regenerative medicine

Epigenetic mechanisms are known to define cell-type identity and function. Hence, reprogramming of one cell type into another essentially requires a rewiring of the underlying epigenome. Cellular reprogramming can convert somatic cells to induced pluripotent stem cells (iPSCs) that can be directed t...

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Pubblicato in:Clin Epigenetics
Autori principali: Basu, Amitava, Tiwari, Vijay K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305869/
https://ncbi.nlm.nih.gov/pubmed/34301318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01131-4
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