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The Role of Voltage-Dependent Anion Channel in Mitochondrial Dysfunction and Human Disease

The voltage-dependent anion channel (VDAC) is a β-barrel membrane protein located in the outer mitochondrial membrane (OMM). VDAC has two conductance states: an open anion selective state, and a closed and slightly cation-selective state. VDAC conductance states play major roles in regulating permea...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Varughese, Joyce T., Buchanan, Susan K., Pitt, Ashley S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305817/
https://ncbi.nlm.nih.gov/pubmed/34359907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071737
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