Human Tissue Angiotensin Converting Enzyme (ACE) Activity Is Regulated by Genetic Polymorphisms, Posttranslational Modifications, Endogenous Inhibitors and Secretion in the Serum, Lungs and Heart

Objective: Inhibitors of the angiotensin converting enzyme (ACE) are the primarily chosen drugs to treat heart failure and hypertension. Moreover, an imbalance in tissue ACE/ACE2 activity is implicated in COVID-19. In the present study, we tested the relationships between circulating and tissue (lun...

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Publicado no:Cells
Main Authors: Bánhegyi, Viktor, Enyedi, Attila, Fülöp, Gábor Áron, Oláh, Attila, Siket, Ivetta Mányiné, Váradi, Csongor, Bottyán, Klaudia, Lódi, Mária, Csongrádi, Alexandra, Umar, Azeem J., Fagyas, Miklós, Czuriga, Dániel, Édes, István, Pólos, Miklós, Merkely, Béla, Csanádi, Zoltán, Papp, Zoltán, Szabó, Gábor, Radovits, Tamás, Takács, István, Tóth, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305685/
https://ncbi.nlm.nih.gov/pubmed/34359878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071708
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