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Hypertrophy of Rat Skeletal Muscle Is Associated with Increased SIRT1/Akt/mTOR/S6 and Suppressed Sestrin2/SIRT3/FOXO1 Levels

Despite the intensive investigation of the molecular mechanism of skeletal muscle hypertrophy, the underlying signaling processes are not completely understood. Therefore, we used an overload model, in which the main synergist muscles (gastrocnemius, soleus) of the plantaris muscle were surgically r...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gombos, Zoltan, Koltai, Erika, Torma, Ferenc, Bakonyi, Peter, Kolonics, Attila, Aczel, Dora, Ditroi, Tamas, Nagy, Peter, Kawamura, Takuji, Radak, Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305659/
https://ncbi.nlm.nih.gov/pubmed/34299206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147588
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