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CD91 Derived Treg Epitope Modulates Regulatory T Lymphocyte Response, Regulates Expression of Costimulatory Molecules on Antigen-Presenting Cells, and Rescues Pregnancy in Mouse Pregnancy Loss Model

The loss of immune tolerance to fetal antigens may result in reproductive failure. The downregulated number and activity of T regulatory lymphocytes, which are critical for the establishment of immune tolerance to fetal antigens, during pregnancy may lead to miscarriage. The adoptive transfer of Tre...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Kedzierska, Anna Ewa, Lorek, Daria, Slawek, Anna, Grabowski, Tomasz, Chelmonska-Soyta, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304956/
https://ncbi.nlm.nih.gov/pubmed/34298914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147296
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