Age-Dependent Hippocampal Proteomics in the APP/PS1 Alzheimer Mouse Model: A Comparative Analysis with Classical SWATH/DIA and directDIA Approaches

Alzheimer’s disease (AD) is the most common neurodegenerative disorder in the human population, for which there is currently no cure. The cause of AD is unknown; however, the toxic effects of amyloid-β (Aβ) are believed to play a role in its onset. To investigate this, we examined changes in global...

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Udgivet i:Cells
Main Authors: van der Spek, Sophie J. F., Gonzalez-Lozano, Miguel A., Koopmans, Frank, Miedema, Suzanne S. M., Paliukhovich, Iryna, Smit, August B., Li, Ka Wan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304546/
https://ncbi.nlm.nih.gov/pubmed/34202490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071588
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