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The Anti-VEGF(R) Drug Discovery Legacy: Improving Attrition Rates by Breaking the Vicious Cycle of Angiogenesis in Cancer

SIMPLE SUMMARY: Several anti-angiogenic drugs have been approved for cancer treatment, alone or in combination with other anti-tumoral agents. Angiogenesis inhibitors cause drug resistance, metastasis formation, and reduced delivery of chemotherapeutic agents, as a consequence of decrease of tumor v...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Ribatti, Domenico, Solimando, Antonio Giovanni, Pezzella, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304542/
https://ncbi.nlm.nih.gov/pubmed/34298648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143433
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