Association between CYP3A5 Polymorphism and Statin-Induced Adverse Events: A Systemic Review and Meta-Analysis

Purpose: Cytochrome P450 (CYP) is involved in the metabolism of statins; CYP3A5 is the main enzyme responsible for lipophilic statin metabolism. However, the evidence of the association between CYP3A5*3 polymorphism and the risk of statin-induced adverse events remains unclear. Therefore, this study...

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Vydáno v:J Pers Med
Hlavní autoři: Yee, Jeong, Kim, Hamin, Heo, Yunhee, Yoon, Ha-Young, Song, Gonjin, Gwak, Hye-Sun
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304457/
https://ncbi.nlm.nih.gov/pubmed/34357144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11070677
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