A Reassessment of Copy Number Variations in Congenital Heart Defects: Picturing the Whole Genome

Copy number variations (CNVs) can modulate phenotypes by affecting protein-coding sequences directly or through interference of gene expression. Recent studies in cancer and limb defects pinpointed the relevance of non-coding gene regulatory elements such as long non-coding RNAs (lncRNAs) and topolo...

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Publicat a:Genes (Basel)
Autors principals: Meerschaut, Ilse, Vergult, Sarah, Dheedene, Annelies, Menten, Björn, De Groote, Katya, De Wilde, Hans, Muiño Mosquera, Laura, Panzer, Joseph, Vandekerckhove, Kristof, Coucke, Paul J., De Wolf, Daniël, Callewaert, Bert
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304049/
https://ncbi.nlm.nih.gov/pubmed/34356064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12071048
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