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Differences in Ovarian and Other Cancers Risks by Population and BRCA Mutation Location

Hereditary breast and ovarian cancer is caused by a germline mutation in BRCA1 or BRCA2 genes. The frequency of germline BRCA1/2 gene mutation carriers and the ratio of germline BRCA1 to BRCA2 mutations in BRCA-related cancer patients vary depending on the population. Genotype and phenotype correlat...

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Bibliografske podrobnosti
izdano v:Genes (Basel)
Main Authors: Sekine, Masayuki, Nishino, Koji, Enomoto, Takayuki
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303997/
https://ncbi.nlm.nih.gov/pubmed/34356066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12071050
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