Development of Randomized Trials in Adults with Medulloblastoma—The Example of EORTC 1634-BTG/NOA-23

SIMPLE SUMMARY: Medulloblastoma is rare after puberty. Among several molecular subgroups that have been described, the sonic hedgehog (SHH) subgroup is highly overrepresented in the post-pubertal population and can be targeted with smoothened (SMO) inhibitors. However, no practice-changing prospecti...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Hau, Peter, Frappaz, Didier, Hovey, Elizabeth, McCabe, Martin G., Pajtler, Kristian W., Wiestler, Benedikt, Seidel, Clemens, Combs, Stephanie E., Dirven, Linda, Klein, Martin, Anazodo, Antoinette, Hattingen, Elke, Hofer, Silvia, Pfister, Stefan M., Zimmer, Claus, Kortmann, Rolf-Dieter, Sunyach, Marie-Pierre, Tanguy, Ronan, Effeney, Rachel, von Deimling, Andreas, Sahm, Felix, Rutkowski, Stefan, Berghoff, Anna S., Franceschi, Enrico, Pineda, Estela, Beier, Dagmar, Peeters, Ellen, Gorlia, Thierry, Vanlancker, Maureen, Bromberg, Jacoline E. C., Gautier, Julien, Ziegler, David S., Preusser, Matthias, Wick, Wolfgang, Weller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303185/
https://ncbi.nlm.nih.gov/pubmed/34298664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143451
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