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Proteases and variants: context matters for SARS-CoV-2 entry assays

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), like other coronaviruses, relies on a flexible array of entry mechanisms, driven by the spike (S) protein. Entry is dependent on proteolytic priming, activation, and receptor binding; all of which can be variable, dependent on context. He...

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Publicat a:Curr Opin Virol
Autors principals: Stevens, Christian S, Oguntuyo, Kasopefoluwa Y, Lee, Benhur
Format: Artigo
Idioma:Inglês
Publicat: Elsevier B.V. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302850/
https://ncbi.nlm.nih.gov/pubmed/34365113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2021.07.004
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