Mechanistic insight into bacterial entrapment by septin cage reconstitution

Septins are cytoskeletal proteins that assemble into hetero-oligomeric complexes and sense micron-scale membrane curvature. During infection with Shigella flexneri, an invasive enteropathogen, septins restrict actin tail formation by entrapping bacteria in cage-like structures. Here, we reconstitute...

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Udgivet i:Nat Commun
Main Authors: Lobato-Márquez, Damián, Xu, Jingwei, Güler, Gizem Özbaykal, Ojiakor, Adaobi, Pilhofer, Martin, Mostowy, Serge
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302635/
https://ncbi.nlm.nih.gov/pubmed/34301939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24721-5
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