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Heterogeneous effects of genetic risk for Alzheimer’s disease on the phenome
Here we report how four major forms of Alzheimer’s disease (AD) genetic risk—APOE-ε4, APOE-ε2, polygenic risk and familial risk—are associated with 273 traits in ~500,000 individuals in the UK Biobank. The traits cover blood biochemistry and cell traits, metabolic and general health, psychosocial he...
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| 出版年: | Transl Psychiatry |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8302633/ https://ncbi.nlm.nih.gov/pubmed/34301914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01518-0 |
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