Emodin alleviates hypertrophic scar formation by suppressing macrophage polarization and inhibiting the Notch and TGF-β pathways in macrophages

Hypertrophic scar (HS) formation is a common complication that develops after skin injury; however, there are few effective and specific therapeutic approaches for HS. Emodin has previously been reported to inhibit mechanical stress-induced HS inflammation. Here, we investigated the molecular mechan...

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Bibliografiske detaljer
Udgivet i:Braz J Med Biol Res
Main Authors: Xia, Zihuan, Wang, Jiancheng, Yang, Songlin, Liu, Cheng, Qin, Shu, Li, Wenbo, Cheng, Yulong, Hu, Huan, Qian, Jin, Liu, Yi, Deng, Chenliang
Format: Artigo
Sprog:Inglês
Udgivet: Associação Brasileira de Divulgação Científica 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302142/
https://ncbi.nlm.nih.gov/pubmed/34320121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X2021e11184
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