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Mechanisms of organophosphate neurotoxicity

The canonical mechanism of organophosphate (OP) neurotoxicity is the inhibition of acetylcholinesterase (AChE). However, multiple lines of evidence suggest that mechanisms in addition to or other than AChE inhibition contribute to the neurotoxic effects associated with acute and chronic OP exposures...

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Detalhes bibliográficos
Publicado no:Curr Opin Toxicol
Main Authors: Tsai, Yi-Hua, Lein, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8302047/
https://ncbi.nlm.nih.gov/pubmed/34308007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cotox.2021.04.002
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