Copper Imbalance in Alzheimer’s Disease: Meta-Analysis of Serum, Plasma, and Brain Specimens, and Replication Study Evaluating ATP7B Gene Variants

Evidence indicates that patients with Alzheimer’s dementia (AD) show signs of copper (Cu) dyshomeostasis. This study aimed at evaluating the potential of Cu dysregulation as an AD susceptibility factor. We performed a meta-analysis of 56 studies investigating Cu biomarkers in brain specimens (pooled...

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Foilsithe in:Biomolecules
Main Authors: Squitti, Rosanna, Ventriglia, Mariacarla, Simonelli, Ilaria, Bonvicini, Cristian, Costa, Alfredo, Perini, Giulia, Binetti, Giuliano, Benussi, Luisa, Ghidoni, Roberta, Koch, Giacomo, Borroni, Barbara, Albanese, Alberto, Sensi, Stefano L., Rongioletti, Mauro
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301962/
https://ncbi.nlm.nih.gov/pubmed/34209820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11070960
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