Copper Imbalance in Alzheimer’s Disease: Meta-Analysis of Serum, Plasma, and Brain Specimens, and Replication Study Evaluating ATP7B Gene Variants

Evidence indicates that patients with Alzheimer’s dementia (AD) show signs of copper (Cu) dyshomeostasis. This study aimed at evaluating the potential of Cu dysregulation as an AD susceptibility factor. We performed a meta-analysis of 56 studies investigating Cu biomarkers in brain specimens (pooled...

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Publicat a:Biomolecules
Autors principals: Squitti, Rosanna, Ventriglia, Mariacarla, Simonelli, Ilaria, Bonvicini, Cristian, Costa, Alfredo, Perini, Giulia, Binetti, Giuliano, Benussi, Luisa, Ghidoni, Roberta, Koch, Giacomo, Borroni, Barbara, Albanese, Alberto, Sensi, Stefano L., Rongioletti, Mauro
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301962/
https://ncbi.nlm.nih.gov/pubmed/34209820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11070960
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