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Receptor Interactions of Angiotensin II and Angiotensin Receptor Blockers—Relevance to COVID-19

Angiotensin II (Ang II) may contain a charge relay system (CRS) involving Tyr/His/carboxylate, which creates a tyrosinate anion for receptor activation. Energy calculations were carried out to determine the preferred geometry for the CRS in the presence and absence of the Arg guanidino group occupyi...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Moore, Graham J., Pires, Jose M., Kelaidonis, Konstantinos, Gadanec, Laura Kate, Zulli, Anthony, Apostolopoulos, Vasso, Matsoukas, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301908/
https://ncbi.nlm.nih.gov/pubmed/34356603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11070979
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