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MiRNA Detection Using a Rolling Circle Amplification and RNA-Cutting Allosteric Deoxyribozyme Dual Signal Amplification Strategy

A microRNA (miRNA) detection platform composed of a rolling circle amplification (RCA) system and an allosteric deoxyribozyme system is proposed, which can detect miRNA-21 rapidly and efficiently. Padlock probe hybridization with the target miRNA is achieved through complementary base pairing and th...

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Detalhes bibliográficos
Publicado no:Biosensors (Basel)
Main Authors: Fang, Chenxin, Ouyang, Ping, Yang, Yuxing, Qing, Yang, Han, Jialun, Shang, Wenyan, Chen, Yubing, Du, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301874/
https://ncbi.nlm.nih.gov/pubmed/34356693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bios11070222
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