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Removal of peptidoglycan and inhibition of active cellular processes leads to daptomycin tolerance in Enterococcus faecalis

Daptomycin is a cyclic lipopeptide antibiotic used in the clinic for treatment of severe enterococcal infections. Recent reports indicate that daptomycin targets active cellular processes, specifically, peptidoglycan biosynthesis. Within, we examined the efficacy of daptomycin against Enterococcus f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Johnston, Rachel D., Woodall, Brittni M., Harrison, Johnathan, Campagna, Shawn R., Fozo, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301656/
https://ncbi.nlm.nih.gov/pubmed/34297729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254796
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