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Type‐2 airway inflammation in mild asthma patients with high blood eosinophils and high fractional exhaled nitric oxide

Type‐2 (T2) inflammation is a characteristic feature of asthma. Biological therapies have been developed to target T2‐inflammation in asthma. IL‐13 is a key component of T2‐inflammation in asthma, driving mucus hypersecretion, IgE‐induction, and smooth muscle contraction. Early phase clinical trials...

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Détails bibliographiques
Publié dans:Clin Transl Sci
Auteurs principaux: Southworth, Thomas, Van Geest, Marleen, Singh, Dave
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301554/
https://ncbi.nlm.nih.gov/pubmed/34106513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.13078
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