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A randomized, double‐blind, placebo‐ and positive‐controlled crossover study of the effects of durlobactam on cardiac repolarization in healthy subjects

Durlobactam (formerly ETX2514) is a diazabicyclooctane β‐lactamase inhibitor that inhibits class A, C, and D β‐lactamases. Sulbactam combined with durlobactam has in vitro and in vivo activity against Acinetobacter baumannii including carbapenem‐ and colistin‐resistant isolates and is being develope...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: O’Donnell, John, Maloney, Kathleen, Steidler, Melissa, Morrison, Royce, Isaacs, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301544/
https://ncbi.nlm.nih.gov/pubmed/33934519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12991
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