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IDH Mutations in Glioma: Double-Edged Sword in Clinical Applications?
Discovery of point mutations in the genes encoding isocitrate dehydrogenases (IDH) in gliomas about a decade ago has challenged our view of the role of metabolism in tumor progression and provided a new stratification strategy for malignant gliomas. IDH enzymes catalyze the conversion of isocitrate...
Shranjeno v:
| izdano v: | Biomedicines |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8301439/ https://ncbi.nlm.nih.gov/pubmed/34356864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9070799 |
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