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TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors

SIMPLE SUMMARY: The Toll-like receptor (TLR) 7 is highly expressed by immune cells including macrophages. Agonists to TLR7 are attractive therapeutic agents as they have the potential of activating both innate and acquired immunity against viral infections. Imiquimod, a specific TLR7 agonist, has be...

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Bibliographic Details
Published in:Biology (Basel)
Main Authors: Meng, Feng-Zhen, Liu, Jin-Biao, Wang, Xu, Wang, Peng, Hu, Wen-Hui, Hou, Wei, Ho, Wen-Zhe
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301371/
https://ncbi.nlm.nih.gov/pubmed/34356516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology10070661
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