Human Trisomic iPSCs from Down Syndrome Fibroblasts Manifest Mitochondrial Alterations Early during Neuronal Differentiation

SIMPLE SUMMARY: Down Syndrome, which is due to the presence of three copies of chromosome 21, always presents with mental retardation, possibly caused by defects in the development of neurons. In recent years, it has been shown that cells and tissues in Down syndrome manifest alterations in the func...

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Detaylı Bibliyografya
Yayımlandı:Biology (Basel)
Asıl Yazarlar: Mollo, Nunzia, Esposito, Matteo, Aurilia, Miriam, Scognamiglio, Roberta, Accarino, Rossella, Bonfiglio, Ferdinando, Cicatiello, Rita, Charalambous, Maria, Procaccini, Claudio, Micillo, Teresa, Genesio, Rita, Calì, Gaetano, Secondo, Agnese, Paladino, Simona, Matarese, Giuseppe, Vita, Gabriella De, Conti, Anna, Nitsch, Lucio, Izzo, Antonella
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301075/
https://ncbi.nlm.nih.gov/pubmed/34209429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology10070609
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