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Targeting cancer with antibody-drug conjugates: Promises and challenges

Antibody-drug conjugates (ADCs) are a rapidly expanding class of biotherapeutics that utilize antibodies to selectively deliver cytotoxic drugs to the tumor site. As of May 2021, the U.S. Food and Drug Administration (FDA) has approved ten ADCs, namely Adcetris®, Kadcyla®, Besponsa®, Mylotarg®, Poli...

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Bibliografische gegevens
Gepubliceerd in:MAbs
Hoofdauteurs: Dean, Alexis Q., Luo, Shen, Twomey, Julianne D., Zhang, Baolin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8300931/
https://ncbi.nlm.nih.gov/pubmed/34291723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2021.1951427
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